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犬胰腺节段性移植伴或不伴胰腺导管结扎

Segmental transplantation of the pancreas with and without the ligation of the duct in dogs.

作者信息

Bartos V, Kolc J, Mattos G, Nozicková M, Vanĕcek R, Málek P

出版信息

Czech Med. 1981;4(1-2):43-8.

PMID:7021098
Abstract

The autotransplantation of a pancreas segment with ligated duct to cervical vessels, autotransplantation and allotransplantation of a pancreas segment with unligated duct to iliac vessels were carried out in three groups of dogs. The occurrence was followed of the hemorrhagic necrosis and of their complications. When ligating the duct, the mortality and the rate of occurrence of hemorrhagic necrosis were of 54 and 77% respectively. In grafts with an open duct into the abdominal cavity, for the autotransplantation the mortality and occurrence of the hemorrhagic necroses were of 33%, for the allotransplantation the mortality and autodigestion were of 11 and 45%, respectively. The cause of the hemorrhagic necrosis in animals with unligated duct of the graft was most probably represented by a hematoma. The graft rejection was characterized by an asymptotic course without damaging the recipient. The transplantation method with open duct into the abdominal cavity is promising for the clinical application.

摘要

将一段胰腺连同结扎的导管自体移植至颈血管,以及将一段胰腺连同未结扎的导管自体移植和同种异体移植至髂血管,在三组犬中进行。观察出血性坏死及其并发症的发生情况。结扎导管时,死亡率和出血性坏死发生率分别为54%和77%。在将导管开放至腹腔的移植物中,自体移植的死亡率和出血性坏死发生率为33%,同种异体移植的死亡率和自体消化率分别为11%和45%。移植物导管未结扎的动物发生出血性坏死的原因很可能是血肿。移植物排斥反应的特点是渐进性过程,不损害受体。将导管开放至腹腔的移植方法在临床应用中很有前景。

相似文献

1
Segmental transplantation of the pancreas with and without the ligation of the duct in dogs.犬胰腺节段性移植伴或不伴胰腺导管结扎
Czech Med. 1981;4(1-2):43-8.
2
Problems in experimental pancreatic segment transplantation with open duct.开放胰管的实验性胰腺节段移植中的问题。
Czech Med. 1985;8(3):167-72.
3
Rat pancreas allotransplantation: a short term comparison of rejection patterns with different methods of exocrine drainage.
J Pathol. 1983 Mar;139(3):259-74. doi: 10.1002/path.1711390304.
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Pancreatic autotransplantation: duct drainage to bladder, duodenum, stomach, compared to duct ligation or free drainage into the peritoneal cavity.胰腺自体移植:导管分别引流至膀胱、十二指肠、胃,并与导管结扎或自由引流至腹腔进行比较。
Transplant Proc. 1982 Dec;14(4):705-8.
5
Role of pancreatic duct ligation for segmental pancreas autotransplantation. Experimental studies.
Transplantation. 1979 Dec;28(6):469-75.
6
Effect of ex vivo hypothermic irradiation on duct-ligated pancreas allografts in dogs: functional, histological, and ultrastructural findings.犬胰管结扎胰腺同种异体移植物的体外低温照射效应:功能、组织学及超微结构研究结果
Am Surg. 1980 Dec;46(12):713-21.
7
Pancreatic transplantation for diabetes mellitus. Discussion of indications and surgical technique with reference to 3 cases.糖尿病的胰腺移植。结合3例病例讨论适应证及手术技术。
Scand J Urol Nephrol. 1975(29 Suppl):63-5.
8
Allogeneic segmental pancreas transplantation in diabetic dogs with and without occlusion of the pancreatic duct.在伴有或不伴有胰管阻塞的糖尿病犬中进行同种异体节段性胰腺移植。
Horm Metab Res Suppl. 1983(13):16-9.
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Duct-ligated versus duct-obliterated canine pancreatic autografts: early postoperative results.导管结扎与导管闭塞的犬胰腺自体移植:术后早期结果
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A simplified technique for segmental pancreas autotransplantation in dogs: exocrine drainage established by pancreatic duct-esophageal anastomosis.犬节段性胰腺自体移植的一种简化技术:通过胰管-食管吻合建立外分泌引流。
Transplant Proc. 1987 Aug;19(4):3501-4.