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糖尿病的胰腺移植。结合3例病例讨论适应证及手术技术。

Pancreatic transplantation for diabetes mellitus. Discussion of indications and surgical technique with reference to 3 cases.

作者信息

Lundgren G, Arnep P, Groth C G, Hårdstedt C, Lewander R, Ringdén O, Ostman J

出版信息

Scand J Urol Nephrol. 1975(29 Suppl):63-5.

PMID:781820
Abstract

Three patients reveived segmental pancreatic transplants. In two the main indication was hyperlabile diabetes, and in the third progressive loss of vision. Vascular anastomoses were to the iliac vessels, the graft being placed extraperitoneally. The pancreatic duct was ligated in the first case, while the other two, the transected end of the pancreatic graft was implanted into a jejunal Roux-Y loop. Two of the patients had normal blood glucose levels without insulin administration for 40 and 35 days, respectively. The grafts then underwent rejection and were removed. In both cases the postoperative course was complicated by pancreatic fistulae. In the 3rd patient the graft failed on the day after operation, due to venous trombosis.

摘要

三名患者接受了节段性胰腺移植。其中两名患者的主要指征是血糖波动过大的糖尿病,第三名患者的主要指征是视力进行性丧失。血管吻合至髂血管,移植物置于腹膜外。第一例患者的胰管被结扎,而另外两例患者,将胰腺移植物的横断端植入空肠 Roux-Y 袢。两名患者分别在未使用胰岛素的情况下血糖水平正常 40 天和 35 天。随后移植物发生排斥反应并被移除。在这两例中,术后病程均因胰瘘而复杂化。在第三名患者中,移植物在术后第二天因静脉血栓形成而失败。

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