Schröder M, von Heyden H W
HNO. 1981 Jul;29(7):225-39.
This review article summarizes the results of cytostatic treatment for squamous carcinoma of the head and neck region between 1977 and 1980. The cytostatic therapy is not established yet. Dosage and combination of the three most effective drugs: Methotrexate, Bleomycin and Cis-Platinum seems to be of minor importance for the effectivity than selection of patients for prognostic factors. Primary chemotherapy in not pretreated patients with Karnofsky-Index above 60% is most successful.
这篇综述文章总结了1977年至1980年间对头颈部鳞状细胞癌进行细胞抑制治疗的结果。细胞抑制疗法尚未确立。对于三种最有效的药物:甲氨蝶呤、博来霉素和顺铂,其剂量和联合使用似乎对疗效的重要性不如根据预后因素选择患者。对卡诺夫斯基指数高于60%的未接受过预处理的患者进行原发性化疗最为成功。