Ruffmann R, Seifert R, Ross H, Sturm E
Laryngol Rhinol Otol (Stuttg). 1982 Jul;61(7):406-10.
25 patients with advanced head-neck-squamous cell carcinoma were treated with a combination of Vindesine and Cis-Platinum. 12 patients were treated before surgery and/or radiation therapy. 25% achieved complete remission. 13 patients were treated for tumour recurrency after prior surgery and/or radiation therapy. 15% achieved C.R. Vindesine/Cis-Platinum is an alternativ scheme to Bleomycin combinations; even after prior RT and CT tumorreduction is frequent. Prior chemotherapy with following surgery and/or radiation therapy is recommended for the treatment of advanced head and neck tumours.
25例晚期头颈部鳞状细胞癌患者接受了长春地辛和顺铂联合治疗。12例患者在手术和/或放疗前接受治疗。25%的患者实现了完全缓解。13例患者在先前手术和/或放疗后因肿瘤复发接受治疗。15%的患者实现了完全缓解。长春地辛/顺铂是博来霉素联合方案的替代方案；即使在先前放疗和化疗后，肿瘤缩小也很常见。对于晚期头颈部肿瘤的治疗，建议先进行化疗，随后进行手术和/或放疗。
