Tarkkanen A, Haltia M
Trans Ophthalmol Soc U K (1962). 1980 Apr;100(Pt 1):151-4.
The eyes of two patients with Creutzfeld-Jakob disease were received at autopsy and examined for any specific changes. Previous clinical examination of one of the patients had failed to reveal any specific ocular changes. No evidence for an infectious agent was found in any portion of the eye. The cornea and the retinal were structurally intact. The axons and the glial elements of the optic nerve head were intact. However, increased cellularity, consisting mainly of astrocytes, was noted in the optic nerves in front of and behind the lamina cribrosa.
两名克雅氏病患者的眼睛在尸检时被获取,并检查是否有任何特定变化。其中一名患者之前的临床检查未发现任何特定的眼部变化。在眼睛的任何部位均未发现感染因子的证据。角膜和视网膜结构完整。视神经乳头的轴突和神经胶质成分完整。然而,在筛板前后的视神经中发现细胞增多,主要由星形胶质细胞组成。