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克雅氏病

Creutzfeld-Jakob disease.

作者信息

Tarkkanen A, Haltia M

出版信息

Trans Ophthalmol Soc U K (1962). 1980 Apr;100(Pt 1):151-4.

PMID:7022776
Abstract

The eyes of two patients with Creutzfeld-Jakob disease were received at autopsy and examined for any specific changes. Previous clinical examination of one of the patients had failed to reveal any specific ocular changes. No evidence for an infectious agent was found in any portion of the eye. The cornea and the retinal were structurally intact. The axons and the glial elements of the optic nerve head were intact. However, increased cellularity, consisting mainly of astrocytes, was noted in the optic nerves in front of and behind the lamina cribrosa.

摘要

两名克雅氏病患者的眼睛在尸检时被获取,并检查是否有任何特定变化。其中一名患者之前的临床检查未发现任何特定的眼部变化。在眼睛的任何部位均未发现感染因子的证据。角膜和视网膜结构完整。视神经乳头的轴突和神经胶质成分完整。然而,在筛板前后的视神经中发现细胞增多,主要由星形胶质细胞组成。

相似文献

1
Creutzfeld-Jakob disease.克雅氏病
Trans Ophthalmol Soc U K (1962). 1980 Apr;100(Pt 1):151-4.
2
[Optical and tactile hallucinosis as clinical onset of Creutzfeld-Jakob disease].
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Panencephalopathic type of Creutzfeldt-Jakob disease with neuropathologic features similar to Pick's disease.具有与匹克氏病相似神经病理学特征的克雅氏病全脑病变型。
Clin Neuropathol. 1993 Jan-Feb;12(1):1-6.
4
Creutzfeldt-Jakob disease and optic atrophy.克雅氏病与视神经萎缩。
Am J Ophthalmol. 1979 Mar;87(3):317-21. doi: 10.1016/0002-9394(79)90070-9.
5
Further ultrastructural studies of lesions produced in the optic nerve by tumor necrosis factor alpha (TNF-alpha): a comparison with experimental Creutzfeldt-Jakob disease.肿瘤坏死因子α(TNF-α)对视神经造成损伤的进一步超微结构研究:与实验性克雅氏病的比较
Acta Neurobiol Exp (Wars). 1994;54(3):209-18.
6
Expression of nestin in ballooned neurons in patients with Creutzfeldt-Jakob disease.
Neurosci Lett. 2004 Aug 12;366(2):144-7. doi: 10.1016/j.neulet.2004.05.033.
7
Virus-simulating structures in the optic nerve head in Creutzfeldt-Jakob disease.克雅氏病中视神经乳头的病毒模拟结构
Am J Ophthalmol. 1979 Jun;87(6):827-33. doi: 10.1016/0002-9394(79)90363-5.
8
Imaging of the optic disc and retinal nerve fiber layer in acute optic neuritis.急性视神经炎中视盘及视网膜神经纤维层的成像
J Neurol Sci. 2006 Dec 1;250(1-2):114-9. doi: 10.1016/j.jns.2006.08.012. Epub 2006 Oct 6.
9
Induction of HLA-DR expression in human lamina cribrosa astrocytes by cytokines and simulated ischemia.细胞因子和模拟缺血诱导人筛板星形胶质细胞中HLA-DR表达
Invest Ophthalmol Vis Sci. 2001 Feb;42(2):365-71.
10
Increased elastin expression in astrocytes of the lamina cribrosa in response to elevated intraocular pressure.筛板星形胶质细胞中弹性蛋白表达增加以响应眼内压升高。
Invest Ophthalmol Vis Sci. 2001 Sep;42(10):2303-14.

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Minimal change prion retinopathy: Morphometric comparison of retinal and brain prion deposits in Creutzfeldt-Jakob disease.微小病变朊病毒视网膜病变:克雅氏病中视网膜和脑部朊病毒沉积的形态计量学比较。
Exp Eye Res. 2022 Sep;222:109172. doi: 10.1016/j.exer.2022.109172. Epub 2022 Jul 6.
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Retinal pigment epithelium translocation and central visual function in age related macular degeneration: preliminary results.年龄相关性黄斑变性中视网膜色素上皮移位与中心视觉功能:初步结果
Int Ophthalmol. 2001;23(4-6):297-307. doi: 10.1023/a:1014482025960.