[降血脂药物氯贝丁酯和苯扎贝特在IIa型和IIb型高脂蛋白血症患者中的比较]
[Comparison of the lipid-lowering agents clofibrate and bezafibrate in patients with hyperlipoproteinemias IIa and IIb].
作者信息
Kokot F, Szczechowska E
出版信息
Z Gesamte Inn Med. 1981 Jul 1;36(13):454-7.
The influence of clofibrate and benzafibrate on total serum cholesterol and triglyceride level was investigated in patients with primary hyperlipoproteinaemia type IIa (16 patients) and IIb (13 patients), following a double-blind protocol. A significant decrease of the triglyceride level in the blood serum was stated in patients with hyperlipoproteinaemia type IIb, treated by benzafibrate. From the results presented in this paper it seems that benzafibrate is especially suitable for the treatment of hyperlipoproteinaemias, characterized by hypertriglyceridaemia.
按照双盲方案，对16例IIa型原发性高脂蛋白血症患者和13例IIb型原发性高脂蛋白血症患者研究了氯贝丁酯和苯扎贝特对血清总胆固醇和甘油三酯水平的影响。苯扎贝特治疗的IIb型高脂蛋白血症患者血清甘油三酯水平显著降低。从本文给出的结果来看，苯扎贝特似乎特别适合治疗以高甘油三酯血症为特征的高脂蛋白血症。
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