Mühlhauser I, Schernthaner G, Seebacher C, Templ H, Ukponmwan O
Acta Med Austriaca. 1981;8(2):48-53.
In the present study we investigated the influence of muscular exercise on stress-hormones (cortisol, growth hormone, epinephrine, norepinephrine) in nonketotic, juvenile-type diabetics (JD) in relation to the degree of metabolic control. The plasma-hormone-concentrations were measured in 8 well controlled JD, 8 moderately controlled JD and in 8 healthy subjects, before, during and after a 30 min bicycle ergometer test of moderate work intensity. The exercise induced rise in cortisol, epinephrine and norepinephrine wa similar in both groups of diabetics and not significantly different compared with controls. In healthy subjects growth hormone levels rose significantly with the onset of exercise, whereas in both patient groups maximal growth hormone concentrations were found at the end of the ergometer test. In moderately controlled JD, however, growth hormone concentrations were significantly higher than in well controlled JD. The results demonstrate that muscular exercise shows a similar effect on cortisol, epinephrine and norepinephrine, but not on growth hormone concentrations in nonketotic, conventionally treated JD compared with controls.
在本研究中，我们调查了肌肉运动对非酮症青少年型糖尿病患者（JD）应激激素（皮质醇、生长激素、肾上腺素、去甲肾上腺素）的影响，并将其与代谢控制程度相关联。在8名血糖控制良好的JD患者、8名血糖中度控制的JD患者以及8名健康受试者中，于中等工作强度的30分钟自行车测力计测试前、测试期间和测试后测量血浆激素浓度。运动诱导的皮质醇、肾上腺素和去甲肾上腺素升高在两组糖尿病患者中相似，与对照组相比无显著差异。在健康受试者中，运动开始时生长激素水平显著升高，而在两组患者中，测力计测试结束时生长激素浓度最高。然而，在血糖中度控制的JD患者中，生长激素浓度显著高于血糖控制良好的JD患者。结果表明，与对照组相比，肌肉运动对非酮症、传统治疗的JD患者的皮质醇、肾上腺素和去甲肾上腺素具有相似的影响，但对生长激素浓度无影响。
