Butson A R
Am J Surg. 1981 Oct;142(4):525-7. doi: 10.1016/0002-9610(81)90391-3.
A prospective randomized trial is described in 119 patients undergoing major abdominal general surgical procedures. Half of the patients were treated prophylactically with intermittent pneumatic calf compression, begun after the induction of anesthesia and continued until the patient was walking; the other half acted as controls. Deep venous thrombosis was detected by iodine-125 fibrinogen scanning and confirmed by venography, and did not differ significantly in the control and treated groups. One fatal pulmonary embolism occurred in each group. The presence of malignancy of the gastrointestinal tract did not influence the results. The findings suggest that pneumatic compression delayed the development of deep venous thrombosis postoperatively and that perhaps it should be continued until discharge from hospital.
一项针对119例行腹部大手术的患者的前瞻性随机试验被描述。一半患者在麻醉诱导后开始接受间歇性气动小腿压迫预防治疗,并持续至患者能行走;另一半作为对照组。通过碘-125纤维蛋白原扫描检测深静脉血栓形成,并通过静脉造影证实,对照组和治疗组之间无显著差异。每组均发生1例致命性肺栓塞。胃肠道恶性肿瘤的存在不影响结果。研究结果表明,气动压迫可延迟术后深静脉血栓形成的发展,也许应持续至出院。