溴隐亭（BCT）对开关现象的影响。

The effect of bromocriptine (BCT) on the on-off phenomenon.

作者信息

Glantz R, Goetz C G, Nausieda P A, Weiner W J, Klawans H L

出版信息

J Neural Transm. 1981;52(1-2):41-7. doi: 10.1007/BF01253095.

Abstract

Twenty-three patients with idiopathic Parkinson disease with classic "on-off" phenomena were studied prospectively during treatment with bromocriptine (BCT). Patients were evaluated for an average of 6 to 12 months and received an average of 56.5 mg of BCT. Nine patients (39%) showed improvement in terms of "on-off". When evaluated retrospectively, it appeared that the only difference between the responders and non-responders was a younger mean age (57.1 to 63.2).

摘要

对23例患有典型“开-关”现象的特发性帕金森病患者在使用溴隐亭（BCT）治疗期间进行了前瞻性研究。患者平均接受评估6至12个月，平均服用56.5毫克BCT。9例患者（39%）在“开-关”方面有改善。回顾性评估时发现，有反应者和无反应者之间唯一的差异是平均年龄较小（57.1至63.2岁）。