Wiesneth M, Pflieger H, Goldmann S F, Arnold R
Vox Sang. 1981;40(6):416-21. doi: 10.1111/j.1423-0410.1981.tb00730.x.
A 23-year-old male patient undergoing first induction chemotherapy for acute myeloid leukaemia received granulocyte transfusions on 10 consecutive days. An average of 2.1 X 10(10) granulocytes was given per square metre body surface area per day. Transfusion reactions and absence of post-transfusion granulocyte increment after the fifth granulocyte transfusion suggested the presence of leukocyte antibodies. However, no antibodies were detectable at this time by the lymphocytotoxicity test, the indirect granulocyte immunofluorescence test, or the platelet suspension immunofluorescence test. In contrast to the clinical observation, the serological detection of leukocyte antibodies was only possible 1 day after the last granulocyte transfusion.
一名23岁男性急性髓系白血病患者正在接受首次诱导化疗，连续10天接受粒细胞输注。每天每平方米体表面积平均输注2.1×10¹⁰个粒细胞。第五次粒细胞输注后出现输血反应且输血后粒细胞未增加，提示存在白细胞抗体。然而，此时通过淋巴细胞毒性试验、间接粒细胞免疫荧光试验或血小板悬液免疫荧光试验均未检测到抗体。与临床观察结果相反，白细胞抗体的血清学检测仅在最后一次粒细胞输注后1天才能进行。
