Hanck A B
Acta Vitaminol Enzymol. 1980;2(5-6):179-85.
Vitamins are playing an increasingly important role in "malattie evolutive", both in the newer sense meaning diseases connected with general development and in the original sense of progressive diseases. Examples of the preventive use of vitamins in certain development phases are the prophylactic administration of vitamin E in premature and new-born babies as protection against retrolental fibroplasia, vitamin K against haemorrhage and vitamin D against bone deformation. Deficient ossification in osteogenesis imperfecta can be prevented by high doses of vitamin C. Recently, greater medical interest has centred around the preventive use of high vitamin dosage in "malattie evolutive" in the original sense. Here, the main interest has been in vitamins E and C which, as recent investigations show, are capable of retarding or preventing deleterious cardiovascular or oncological diseases.
维生素在“进行性疾病”中发挥着越来越重要的作用,这一概念既有与一般发育相关疾病的新含义,也有其渐进性疾病的原始意义。在某些发育阶段预防性使用维生素的例子包括:对早产儿和新生儿预防性给予维生素E以预防晶状体后纤维增生,给予维生素K预防出血,给予维生素D预防骨骼变形。大剂量维生素C可预防成骨不全症中的骨化不足。最近,医学上更多的兴趣集中在从原始意义上对“进行性疾病”预防性使用高剂量维生素。在此,主要关注的是维生素E和C,最近的研究表明,它们能够延缓或预防有害的心血管疾病或肿瘤疾病。