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[人类胚胎前白蛋白-2的动物类似物]

[Animal analogs of human embryonal prealbumin-2].

作者信息

Kalashnikov V V, Falaleeva D M, Tatarinov Iu S

出版信息

Biull Eksp Biol Med. 1981 Jul;92(7):62-4.

PMID:7028166
Abstract

Immunochemical analogs of human embryonal prealbumin-2 (EPA-2) were found in blood sera and amniotic fluid of the cow, sheep and pig fetuses. Meanwhile they were not detected in blood sera of adult animals. Analogs of animal EPA-2 produced the reaction of complete immunochemical identity with human EPA-2. Moreover, they have similar physicochemical properties and electrophoretic mobility of prealbumins. The indirect immunofluorescence technique was used to locate EPA-2 in collagenic fibres of fetuses and in adult animals' connective tissue. It is suggested that EPA-2 might be the protein contained by procollagen or by non-collagenic components of collagenic fibres.

摘要

在牛、羊和猪胎儿的血清及羊水中发现了人类胚胎前白蛋白-2(EPA-2)的免疫化学类似物。同时,在成年动物的血清中未检测到它们。动物EPA-2的类似物与人类EPA-2产生了完全免疫化学同一性反应。此外,它们具有相似的物理化学性质和前白蛋白的电泳迁移率。采用间接免疫荧光技术在胎儿的胶原纤维和成年动物的结缔组织中定位EPA-2。有人提出,EPA-2可能是原胶原或胶原纤维的非胶原成分所含的蛋白质。

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