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在家自行使用氟化物的价值。

The value of self-applied fluorides at home.

作者信息

Holloway P J, Levine R S

出版信息

Int Dent J. 1981 Sep;31(3):232-9.

PMID:7028640
Abstract

Dental research workers from several scientific disciplines have combined over the years to give much greater insight into the basic mechanisms whereby fluoride protects the teeth against dental decay. These basic investigations have enabled clinical research workers to test new fluoride delivery systems rationally rather than empirically, and it now seems that two entirely different modes need to be combined to form maximum protection. First, fluoride ions need to be introduced at the correct level into the forming enamel crystals during tooth development; secondly, fluoride ions need to be present at optimal concentrations at the plague-enamel interface during active carious attack. Both these situations require low levels of fluoride concentration to be delivered to the subject at very regular intervals. Water fluoridation is the best method of achieving this situation, but in the absence of this important public health measure, dental scientists have developed a battery of other vehicles which, when used on a daily basis at home, will have a considerable impact on caries activity. While further work continues to improve the effectiveness of these techniques, enough has been achieved already to encourage their use by the general public. What are required now are the necessary skills in health politics and behavioral science to gain public acceptance and application of these endeavours.

摘要

多年来,来自多个科学学科的牙科研究人员联合起来,对氟化物保护牙齿免受龋齿侵害的基本机制有了更深入的了解。这些基础研究使临床研究人员能够合理而非凭经验地测试新的氟化物输送系统,现在看来,两种截然不同的方式需要结合起来以形成最大程度的保护。首先,在牙齿发育过程中,氟离子需要以正确的水平引入正在形成的釉质晶体中;其次,在活跃的龋齿攻击期间,氟离子需要以最佳浓度存在于菌斑 - 釉质界面。这两种情况都需要以非常规律的间隔向受试者输送低水平的氟化物浓度。水氟化是实现这种情况的最佳方法,但在没有这项重要的公共卫生措施的情况下,牙科科学家已经开发出一系列其他载体,当在家中每天使用时,将对龋齿活动产生相当大的影响。虽然进一步的工作仍在继续提高这些技术的有效性,但已经取得了足够的成果来鼓励公众使用。现在需要的是健康政策和行为科学方面的必要技能,以获得公众对这些努力的接受和应用。

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