Foltzer C, Harvey S, Strosser M T, Mialhe P
J Endocrinol. 1981 Nov;91(2):189-96. doi: 10.1677/joe.0.0910189.
An inverse age-related pattern of GH secretion has been identified in immature ducks between 2 and 9 weeks of age, the plasma level of GH falling progressively from 30-40 ng/ml at 2 weeks of age to the adult level (less than 10 ng/ml) by 9 weeks of age. This decrease in GH secretion was not accompanied by any age-related changes in the concentrations of plasma immunoreactive insulin of glucagon-like immunoreactivity or in plasma glucose or free fatty acid level. In 4- to 6-week-old ducklings the intravenous infusion of insulin (2.5 or 10 mu./kg per min for 30 min) and glucagon (0.1 or 0.5 micrograms/kg per min for 30 min) induced some inhibition of GH secretion, independently of changes in blood glucose level. These results suggest that although insulin and especially glucagon have direct effects on GH secretion in the duck, maturational differences in pancreatic function are unlikely to be causally related to the decrease in GH secretion during growth.
在2至9周龄的未成熟鸭中已发现生长激素（GH）分泌呈现与年龄相关的相反模式，血浆GH水平从2周龄时的30 - 40 ng/ml逐渐下降，到9周龄时降至成年水平（低于10 ng/ml）。GH分泌的这种减少并未伴随着血浆免疫反应性胰岛素、胰高血糖素样免疫反应性浓度、血浆葡萄糖或游离脂肪酸水平的任何与年龄相关的变化。在4至6周龄的雏鸭中，静脉输注胰岛素（2.5或10 μ/kg每分钟，持续30分钟）和胰高血糖素（0.1或0.5 μg/kg每分钟，持续30分钟）会独立于血糖水平变化而对GH分泌产生一定抑制作用。这些结果表明，尽管胰岛素尤其是胰高血糖素对鸭的GH分泌有直接影响，但胰腺功能的成熟差异不太可能与生长过程中GH分泌的减少存在因果关系。
