用大肠杆菌热稳定肠毒素免疫的大鼠中的保护作用。
Protection in rats immunized with Escherichia coli heat-stable enterotoxin.
作者信息
Klipstein F A, Engert R F, Clements J D
出版信息
Infect Immun. 1981 Nov;34(2):637-9. doi: 10.1128/iai.34.2.637-639.1981.
Abstract
Rats immunized with a semipurified preparation of the Escherichia coli heat-stable (ST) enterotoxin conjugated with a protein carrier were protected against challenge with semipurified or purified ST and viable organisms of multiple heterologous serotypes that produce only ST (LT-/ST+), but they were not protected against heal-labile (LT) toxin or viable strains which produce LT either alone (LT+/ST-) or together with ST (LT+/ST+).
摘要
用与蛋白质载体偶联的大肠杆菌热稳定（ST）肠毒素的半纯化制剂免疫的大鼠，可抵御半纯化或纯化的ST以及多种仅产生ST的异源血清型活生物体（LT-/ST+）的攻击，但它们不能抵御不耐热（LT）毒素或单独产生LT（LT+/ST-）或与ST一起产生LT（LT+/ST+）的活菌株的攻击。
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