β-甲基正亮氨酸，一种由粘质沙雷氏菌产生的抗代谢物。

beta-methylnorleucine, an antimetabolite produced by Serratia marcescens.

作者信息

Sugiura M, Kisumi M, Chibata I

出版信息

J Antibiot (Tokyo). 1981 Oct;34(10):1278-82. doi: 10.7164/antibiotics.34.1278.

DOI:10.7164/antibiotics.34.1278

Abstract

An amino acid was formed by alpha-aminobutyrate-resistant mutants of Serratia marcescens grown in a medium containing norvaline. This amino acid was identified as erythro-beta-methyl-L-norleucine [(2S,3S)-2-amino-3-methylhexanoic acid] by instrumental analyses. beta-Methylnorleucine inhibited the growth of several bacteria in synthetic medium.

摘要

在含有正缬氨酸的培养基中生长的粘质沙雷氏菌的α-氨基丁酸抗性突变体形成了一种氨基酸。通过仪器分析，这种氨基酸被鉴定为赤藓糖型-β-甲基-L-正亮氨酸[（2S，3S）-2-氨基-3-甲基己酸]。β-甲基正亮氨酸在合成培养基中抑制了几种细菌的生长。