Kisumi M, Sugiura M, Chibata I
Appl Environ Microbiol. 1977 Aug;34(2):135-8. doi: 10.1128/aem.34.2.135-138.1977.
A norleucine-resistant mutant was derived from an isoleucine-valine auxotroph of a leucine accumulator of Serratia marcescens. The norleucine-resistant mutant could accumulate norleucine from norvaline in the medium without the addition of methionine, which antagonized norleucine. This mutant constitutively formed homoserine-O-transsuccinylase.
一株正亮氨酸抗性突变体源自粘质沙雷氏菌亮氨酸积累菌株的异亮氨酸 - 缬氨酸营养缺陷型。该正亮氨酸抗性突变体在不添加拮抗正亮氨酸的甲硫氨酸的情况下,能够从培养基中的正缬氨酸积累正亮氨酸。此突变体组成型地形成高丝氨酸 - O - 转琥珀酰酶。