Beezer A E, Sharma P B
Microbios. 1981;30(121-122):139-51.
The uptake of nystatin by sensitive Saccharomyces cerevisiae cells has been studied as a function of temperature and nystatin concentration. Following analysis of the data, kinetic rate constants and a monolayer capacity are calculated. This shows that c 13 X more nystatin is taken up than can be supported by the cell surface. The process is accompanied by an activation energy of 41.6 kJ mol-1. It is suggested that these data support a rapid uptake process onto the cell wall followed by a slower diffusion process through the wall to the membrane.
已研究了敏感型酿酒酵母细胞对制霉菌素的摄取情况，该摄取是温度和制霉菌素浓度的函数。对数据进行分析后，计算出动力学速率常数和单层容量。结果表明，摄取的制霉菌素比细胞表面所能容纳的量多13倍。该过程的活化能为41.6 kJ/mol。有人认为，这些数据支持制霉菌素先快速摄取到细胞壁上，然后再通过细胞壁缓慢扩散到细胞膜的过程。
