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实验啮齿动物宿主中的原发性和继发性皮肤利什曼病

Primary and secondary skin leishmaniasis in experimental rodent hosts.

作者信息

Krampitz H E

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1981;250(1-2):191-7.

PMID:7032148
Abstract

Pathological observations are described from experimental infections of Syrian hamsters, nude mice and bank voles with different Leishmania strains isolated from travellers returning to Germany from endemic areas. The main purpose of the paper was to demonstrate the changing patterns of parasite predilection sites within appropriate experimental animals. Despite the occasionally-occurring episodes of altered predilection sites the principal organotropic behaviour of given Leishmania strain was remarkably constant in in vivo passages. Here a genetic background seems evident which justified a legal use of such host related properties in taxonomic considerations. It was noted that humans appear to be poor indicators of the micro-ecological abilities of Leishmania spp.

摘要

本文描述了从流行地区返回德国的旅行者身上分离出的不同利什曼原虫菌株对叙利亚仓鼠、裸鼠和棕背田鼠进行实验性感染后的病理学观察结果。本文的主要目的是证明在合适的实验动物体内寄生虫偏好部位的变化模式。尽管偶尔会出现偏好部位改变的情况,但特定利什曼原虫菌株的主要器官嗜性在体内传代过程中非常稳定。这里似乎有明显的遗传背景,这使得在分类学考虑中合法利用这种与宿主相关的特性成为可能。值得注意的是,人类似乎是利什曼原虫属微生态能力的不良指示物。

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