Vaillant J M, Laudenbach P, Schuller E, Muller J Y, Deboise A
Ann Med Interne (Paris). 1981;132(6):408-12.
Two univitelline twin sisters developed Gougerot-Sjögren's syndrome at 30 years of age. Immunity disorders were more significant in the sister with the more severe disorder, as demonstrated by sialography and scintigraphy. Among the immunological tests practiced, emphasis is placed on antinuclear antibody assay in the saliva, the authors finding no mention of this test in the published literature. Of particular interest is the negative result of histological examination of the accessory salivary glands, this contrasting with the close relationship between immunity and sialographic disturbances. The identical nature of the two sisters was confirmed by a study of the HLA systems, but this did not demonstrate the presence of the B8 marker, classically correlated with Gougerot-Sjögren's syndrome.
两名单卵双生姐妹在30岁时患上了舍格伦综合征。唾液造影和闪烁扫描显示，病情较重的姐妹免疫紊乱更为明显。在所进行的免疫学检测中，重点是唾液中的抗核抗体检测，作者在已发表的文献中未发现提及此项检测。特别值得关注的是副唾液腺组织学检查结果为阴性，这与免疫和唾液造影异常之间的密切关系形成对比。通过对HLA系统的研究证实了两姐妹的同卵性质，但这并未显示出与舍格伦综合征经典相关的B8标记物的存在。
