Sotnikov O S, Iashin V A, Karnaukhov V N
Arkh Anat Gistol Embriol. 1981 Aug;81(8):41-50.
Heterogeneity in distribution of the dry substance mass (protein) in normal and reactively altered isolated neurons has been studied in vital investigations by means of interference microscopy and microspectrophotometry. It has been demonstrated that at a reactive reconstruction neuroplasmic substances undergo rearrangement, resulting in increased heterogeneity. In peripheral juxtamembranous parts neuroplasmic colloids are divided separating the hydrated zone with a low content of protein and forming made that an increasing adhesion of the juxtamembranous proteins could result in their aggregation with protein complexes of the transmembranous ionic canals, that affects the specific electrogencic function of the neuron.
在活体研究中,借助干涉显微镜和显微分光光度法,对正常和反应性改变的孤立神经元中干物质质量(蛋白质)的分布异质性进行了研究。结果表明,在反应性重建过程中,神经质物质会发生重排,导致异质性增加。在周边近膜部分,神经质胶体被分隔开,形成了一个蛋白质含量低的水合区域,并且近膜蛋白质的粘附增加可能导致它们与跨膜离子通道的蛋白质复合物聚集,从而影响神经元的特定生电功能。