• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Cell culture studies on patients with extreme insulin resistance. I. Receptor defects on cultured fibroblasts.

作者信息

Podskalny J M, Kahn C R

出版信息

J Clin Endocrinol Metab. 1982 Feb;54(2):261-8. doi: 10.1210/jcem-54-2-261.

DOI:10.1210/jcem-54-2-261
PMID:7033276
Abstract
摘要

相似文献

1
Cell culture studies on patients with extreme insulin resistance. I. Receptor defects on cultured fibroblasts.极端胰岛素抵抗患者的细胞培养研究。I. 培养成纤维细胞的受体缺陷。
J Clin Endocrinol Metab. 1982 Feb;54(2):261-8. doi: 10.1210/jcem-54-2-261.
2
Cell culture studies on patients with extreme insulin resistance. II. Abnormal biological responses in cultured fibroblasts.极端胰岛素抵抗患者的细胞培养研究。II. 培养成纤维细胞中的异常生物学反应。
J Clin Endocrinol Metab. 1982 Feb;54(2):269-75. doi: 10.1210/jcem-54-2-269.
3
Demonstration of a primary (? genetic) defect in insulin receptors in fibroblasts from a patient with the syndrome of insulin resistance and acanthosis nigricans type A.一名患有A型胰岛素抵抗和黑棘皮症综合征患者的成纤维细胞中胰岛素受体原发性（可能为遗传性）缺陷的证明。
J Clin Endocrinol Metab. 1980 Jun;50(6):1139-41. doi: 10.1210/jcem-50-6-1139.
4
Autophosphorylation of cultured skin fibroblast insulin receptors from patients with severe insulin resistance and acanthosis nigricans.严重胰岛素抵抗和黑棘皮病患者培养的皮肤成纤维细胞胰岛素受体的自磷酸化
Diabetes. 1989 Mar;38(3):328-32. doi: 10.2337/diab.38.3.328.
5
Acromegaloid patients with type A insulin resistance: parallel defects in insulin and insulin-like growth factor-I receptors and biological responses in cultured fibroblasts.A型胰岛素抵抗的肢端肥大症样患者：胰岛素和胰岛素样生长因子-I受体的平行缺陷及培养成纤维细胞中的生物学反应
J Clin Endocrinol Metab. 1989 Aug;69(2):329-37. doi: 10.1210/jcem-69-2-329.
6
[Insulin receptors in syndromes involving acanthosis nigricans and severe insulin resistance].[涉及黑棘皮病和严重胰岛素抵抗综合征中的胰岛素受体]
G Ital Dermatol Venereol. 1982 Mar-Apr;117(2):73-82.
7
Insulin receptors, acanthosis nigricans, and insulin resistance.胰岛素受体、黑棘皮病与胰岛素抵抗
Lancet. 1986 Mar 15;1(8481):595-6.
8
Insulin resistance, acanthosis nigricans, and normal insulin receptors in a young woman: evidence for a postreceptor defect.一名年轻女性的胰岛素抵抗、黑棘皮症与正常胰岛素受体：受体后缺陷的证据
J Clin Endocrinol Metab. 1978 Sep;47(3):620-5. doi: 10.1210/jcem-47-3-620.
9
Defects in insulin binding and autophosphorylation of erythrocyte insulin receptors in patients with syndromes of severe insulin resistance and their parents.重度胰岛素抵抗综合征患者及其父母红细胞胰岛素受体的胰岛素结合和自身磷酸化缺陷
J Clin Endocrinol Metab. 1987 Mar;64(3):549-56. doi: 10.1210/jcem-64-3-549.
10
Identification of a receptor for somatomedin-like polypeptides in human fibroblasts.人成纤维细胞中类生长调节素多肽受体的鉴定
J Clin Endocrinol Metab. 1977 May;44(5):820-31. doi: 10.1210/jcem-44-5-820.

引用本文的文献

1
Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function.人类诱导多能干细胞中的胰岛素抵抗会降低线粒体大小和功能。
Sci Rep. 2016 Mar 7;6:22788. doi: 10.1038/srep22788.
2
Severe insulin resistance alters metabolism in mesenchymal progenitor cells.严重胰岛素抵抗会改变间充质祖细胞的代谢。
Endocrinology. 2015 Jun;156(6):2039-48. doi: 10.1210/en.2014-1403. Epub 2015 Mar 26.
3
Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications.胰岛素抵抗与多囊卵巢综合征再探：机制与意义的最新进展。
Endocr Rev. 2012 Dec;33(6):981-1030. doi: 10.1210/er.2011-1034. Epub 2012 Oct 12.
4
Insulin binding and activation of glycogen synthase in fibroblasts from Type 1 (insulin-dependent) diabetic patients.1型（胰岛素依赖型）糖尿病患者成纤维细胞中胰岛素与糖原合酶的结合及激活
Diabetologia. 1982 Nov;23(5):431-5. doi: 10.1007/BF00260957.
5
Insulin receptor degradation is accelerated in cultured lymphocytes from patients with genetic syndromes of extreme insulin resistance.在患有极端胰岛素抵抗遗传综合征患者的培养淋巴细胞中，胰岛素受体降解加速。
J Clin Invest. 1984 Oct;74(4):1366-74. doi: 10.1172/JCI111547.
6
Pancreatic A and B cell hyperfunction in the Mendenhall syndrome.门登霍尔综合征中的胰腺A细胞和B细胞功能亢进。
Diabetologia. 1983 Jul;25(1):8-12. doi: 10.1007/BF00251888.
7
Pathogenetic mechanisms of hereditary diabetes mellitus.遗传性糖尿病的发病机制。
Hum Genet. 1983;63(2):100-6. doi: 10.1007/BF00291526.
8
Mechanisms of insulin resistance in cultured fibroblasts from a patient with leprechaunism: resistance to proteolytic activation of glycogen synthase by trypsin.一名妖精貌综合征患者培养的成纤维细胞中胰岛素抵抗的机制：对胰蛋白酶介导的糖原合酶蛋白水解激活的抵抗。
Mol Cell Biochem. 1985 Mar;66(2):117-25. doi: 10.1007/BF00220779.
9
Structural analysis of normal and mutant insulin receptors in fibroblasts cultured from families with leprechaunism.对来自妖精貌综合征家族培养的成纤维细胞中正常和突变胰岛素受体的结构分析。
Am J Hum Genet. 1987 Sep;41(3):402-17.
10
The insulin receptor concept and its relation to the treatment of diabetes.胰岛素受体概念及其与糖尿病治疗的关系。
Drugs. 1987 Feb;33(2):156-70. doi: 10.2165/00003495-198733020-00004.