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噬菌体T5的早期前基因产物对大肠杆菌RNA聚合酶的修饰作用。

Modification of RNA polymerase from Escherichia coli by pre-early gene products of bacteriophage T5.

作者信息

McCorquodale D J, Chen C W, Joseph M K, Woychik R

出版信息

J Virol. 1981 Dec;40(3):958-62. doi: 10.1128/JVI.40.3.958-962.1981.

DOI:10.1128/JVI.40.3.958-962.1981
PMID:7033565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC256710/
Abstract

RNA polymerase from cells of Escherichia coli infected with T5 were recovered as a complex with two pre-early phage-coded polypeptides, the 60,000-dalton product of gene A1 and a previously reported 11,000-dalton polypeptide. This RNA polymerase complex had altered transcriptional specificity, in that it transcribed pre-early genes less efficiently than it did early genes.

摘要

从感染了T5噬菌体的大肠杆菌细胞中回收的RNA聚合酶，是与两种前早期噬菌体编码的多肽形成的复合物，即基因A1的60000道尔顿产物和先前报道的11000道尔顿多肽。这种RNA聚合酶复合物具有改变的转录特异性，即它转录前早期基因的效率低于转录早期基因的效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/256710/a8f52a66fabf/jvirol00165-0346-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/256710/a8f52a66fabf/jvirol00165-0346-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/256710/a8f52a66fabf/jvirol00165-0346-a.jpg

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