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Tobacco-alcohol amblyopia: a proposed biochemical basis for pathogenesis.

作者信息

Dang C V

出版信息

Med Hypotheses. 1981 Nov;7(11):1317-28. doi: 10.1016/0306-9877(81)90122-5.

DOI:10.1016/0306-9877(81)90122-5
PMID:7033739
Abstract

Tobacco-alcohol or nutritional amblyopia is a rare disorder of decreased central vision associated with nutritional deficiencies and tobacco smoking. although folate deficiency is common in patients with tobacco-alcohol amblyopia, the role of folic acid in this disorder has been underplayed. The role of cyanide from tobacco smoke, folate and other dietary deficiencies will be reviewed. A new model of the pathogenesis of tobacco-alcohol amblyopia is proposed based on the presumptive alteration of methionine and S-adenosyl-L-methionine metabolism.

摘要

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