Kupersmith M J, Weiss P A, Carr R E
Am J Ophthalmol. 1983 Mar;95(3):307-14. doi: 10.1016/s0002-9394(14)78298-4.
Twelve subjects, nine with tobacco-alcohol amblyopia and three with nutritional amblyopia, were studied with pattern and flash visual-evoked potentials. We found abnormal steady-state responses in all 12 patients, including those with minor visual abnormalities, when the contrast of the stimulus was decreased. The latency of the first major positive wave (P100) of the flash- or pattern-evoked potential was not delayed in 11 of the 12 patients. The normal P100 latencies differed from the prolonged latencies found in other patients with loss of central nervous system myelin caused by vitamin B12 deficiency or multiple sclerosis.
对12名受试者进行了图形和闪光视觉诱发电位研究，其中9名患有烟酒性弱视，3名患有营养性弱视。我们发现，当刺激对比度降低时，所有12名患者，包括那些有轻微视力异常的患者，均出现异常稳态反应。12名患者中有11名的闪光或图形诱发电位的第一个主要正波（P100）潜伏期未延迟。正常的P100潜伏期与其他因维生素B12缺乏或多发性硬化症导致中枢神经系统髓鞘脱失的患者所发现的延长潜伏期不同。
