Endoh M, Kaneshige H, Tomino Y, Nomoto Y, Sakai H, Arimori S, Shinbo T, Ishihara T
Tokai J Exp Clin Med. 1981 Oct;6(4):421-5.
A 29-year-old male patient with IgA nephropathy developed scleritis and myasthenia gravis during the follow-up period. No lymphocytic infiltration or atrophy in muscle fibers was observed in muscle biopsy specimens. However, an immunofluorescent study on the same specimens showed deposits of immunoglobulin A in muscular vessels. The development of scleritis and myasthenia gravis in a patient with IgA nephropathy suggests a common immunologic basis for these disorders.
一名29岁的IgA肾病男性患者在随访期间出现了巩膜炎和重症肌无力。肌肉活检标本中未观察到淋巴细胞浸润或肌纤维萎缩。然而，对同一标本进行的免疫荧光研究显示肌肉血管中有免疫球蛋白A沉积。IgA肾病患者出现巩膜炎和重症肌无力提示这些疾病存在共同的免疫基础。
