Miyazaki M, Kimura N, Imai K, Eguchi K, Yagame M, Miura M, Endoh M, Tomino Y, Nomoto Y, Sakai H
Department of Internal Medicine, School of Medicine, Tokai University, Kanagawa-Ken, Japan.
Nephron. 1989;51(3):402-4. doi: 10.1159/000185331.
Three patients with IgA nephropathy associated with myasthenia gravis are described. In all 3 cases, myasthenia gravis emerged after the discovery of glomerulonephritis. Myasthenic symptoms were improved by thymectomy in 2 cases, but progression of the renal disease was not improved. Some systemic abnormalities, including immunological aberrations, were observed in these two disorders. It is postulated that T cell abnormalities in IgA nephropathy might be independent of the development of myasthenia gravis.
本文描述了3例与重症肌无力相关的IgA肾病患者。在所有3例患者中，重症肌无力均在肾小球肾炎被发现之后出现。2例患者经胸腺切除术后肌无力症状得到改善，但肾脏疾病的进展并未改善。在这两种疾病中均观察到一些全身异常，包括免疫异常。据推测，IgA肾病中的T细胞异常可能与重症肌无力的发生无关。
