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牛II型全身性糖原贮积病中的骨骼肌α-葡萄糖苷酶

Skeletal-muscle alpha-glucosidases in bovine generalized glycogenosis type II.

作者信息

Dorling P R, Howell J M, Gawthorne J M

出版信息

Biochem J. 1981 Aug 15;198(2):409-12. doi: 10.1042/bj1980409.

DOI:10.1042/bj1980409
PMID:7034730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1163264/
Abstract

The skeletal muscle of cattle suffering from generalized glycogenosis type II was shown to lack acid alpha-glucosidase (EC 3.2.1.3) activity. Furthermore, there was no evidence of enzymically inactive proteins that cross-reacted with antibodies raised against acid alpha-glucosidase from the muscle of normal animals.

摘要

患II型全身性糖原贮积症牛的骨骼肌显示缺乏酸性α-葡萄糖苷酶（EC 3.2.1.3）活性。此外，没有证据表明存在与针对正常动物肌肉中酸性α-葡萄糖苷酶产生的抗体发生交叉反应的无酶活性蛋白。

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Bovine generalised glycogenosis type II. Uptake of lysosomal alpha-glucosidase by cultured skeletal muscle and reversal of glycogen accumulation.
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Acta Neuropathol. 1982;58(1):64-8. doi: 10.1007/BF00692699.
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本文引用的文献

1
INBORN LYSOSOMAL DISEASES.先天性溶酶体病
Gastroenterology. 1965 May;48:625-33.
2
AN ELECTRON MICROSCOPIC AND BIOCHEMICAL STUDY OF TYPE II GLYCOGENOSIS.II型糖原贮积病的电子显微镜及生化研究
Lab Invest. 1964 Sep;13:1139-52.
3
alpha-Glucosidase deficiency in generalized glycogenstorage disease (Pompe's disease).全身性糖原贮积病（庞贝氏病）中的α-葡萄糖苷酶缺乏症。
Biochem J. 1963 Jan;86(1):11-6. doi: 10.1042/bj0860011.
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Biochemical studies on a case of feline mannosidosis.一例猫甘露糖苷贮积症的生化研究
Biochem J. 1980 Sep 1;189(3):467-73. doi: 10.1042/bj1890467.
5
Acid alpha-D-glucosidase glucohydrolase from cattle liver.来自牛肝脏的酸性α-D-葡萄糖苷酶葡萄糖水解酶。
J Biol Chem. 1969 Sep 10;244(17):4735-42.
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Rodent and human acid -glucosidase. Purification, properties and inhibition by antibodies. Investigation in type II glycogenosis.啮齿动物和人类的酸性葡萄糖苷酶。纯化、特性及抗体抑制作用。II型糖原贮积病的研究。
Eur J Biochem. 1972 Nov 21;31(1):156-65. doi: 10.1111/j.1432-1033.1972.tb02514.x.
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Molecular studies on glycogen storage diseases.糖原贮积病的分子研究
Enzyme. 1974;18(1):60-72. doi: 10.1159/000459414.
8
Characterization of human liver alpha-D-mannosidase purified by affinity chromatography.通过亲和层析纯化的人肝脏α-D-甘露糖苷酶的特性分析。
Biochem J. 1976 Mar 1;153(3):579-87. doi: 10.1042/bj1530579.
9
Toward enzyme therapy for lysosomal storage diseases.迈向溶酶体贮积症的酶疗法。
Physiol Rev. 1976 Jan;56(1):57-99. doi: 10.1152/physrev.1976.56.1.57.
10
Characterization of the mutant alpha-mannosidase in bovine mannosidosis.牛甘露糖苷贮积症中突变α-甘露糖苷酶的特征分析
Biochem J. 1978 Dec 1;175(3):1013-22. doi: 10.1042/bj1751013.