Molyneux A J, Sheldon P W
Br J Radiol. 1982 Feb;55(650):117-9. doi: 10.1259/0007-1285-55-650-117.
A randomized blind trial of iopamidol and meglumine calcium metrizoate (Triosil 280, Isopaque Cerebral) for cerebral angiography was performed in 20 patients. The Iopamidol was better tolerated and caused significantly less discomfort in patients than metrizoate. There was no difference in the quality of the radiographs. A further 13 patients also received Iopamidol for cerebral angiography with similar results. No adverse effects were observed in any of the patients. Our evidence suggests that Iopamidol has significant advantages over currently available contrast media for cerebral angiography.
对20例患者进行了碘帕醇和甲泛葡胺（碘曲仑280、异泛影葡胺）用于脑血管造影的随机盲法试验。与甲泛葡胺相比，碘帕醇耐受性更好，给患者带来的不适明显更少。X光片质量无差异。另外13例患者也接受了碘帕醇脑血管造影，结果相似。所有患者均未观察到不良反应。我们的证据表明，在脑血管造影方面，碘帕醇比目前可用的造影剂具有显著优势。
