Schollmayer E, Schäfer D, Frisch B, Schleiermacher E
Hum Genet. 1981;59(3):187-93. doi: 10.1007/BF00283661.
Human prophase, premetaphase, and mid-metaphase chromosomes are prepared and analyzed using the thymidine cell synchronization technique and R-banding patterns (RBA). Haploid sets with 700-1000 bands can be demonstrated. Sequences of chromosomes of different degrees of condensation are helpful for a better understanding and classification of regions of extended chromosomes. A considerable variation in the condensation of parts of homologous chromosomes is reflected in the variability of the arm ratio. This differential condensation of chromosomes is entirely effected by variation of the degree of condensation in AT rich interbands and can be attributed to the degree of labeling by BrdU.
利用胸腺嘧啶核苷细胞同步化技术和R带模式（RBA）制备并分析人类前期、前中期和中期染色体。可以展示出具有700 - 1000条带的单倍体组。不同凝聚程度的染色体序列有助于更好地理解和分类伸展染色体的区域。同源染色体部分凝聚程度的显著差异反映在臂比的变异性上。染色体的这种差异凝聚完全是由富含AT的间带凝聚程度的变化所导致的，并且可归因于5-溴脱氧尿嘧啶核苷（BrdU）的标记程度。
