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[高压氧治疗期间咽部细菌菌群的变化]

[Changes in the pharyngeal bacterial flora during hyperbaric oxygenation].

作者信息

Ulewicz K, Zannini D, Varaldo P, Wolanska M, Formai C, Assmann A

出版信息

Minerva Med. 1981 Dec 30;72(52):3589-93.

PMID:7036004
Abstract

Qualitative and quantitative bacteriological tests of throat smears were carried out on the following three groups of patients: 1) Patients exposed to several 90-minute sequences of oxygen hyperbaria, at a height of 2.2 ata O2, at intervals of 2 to 3 days. 2) Patients exposed to a single 30-minute dose of oxygen hyperbaria at a height of 2.5 ata O2/the oxygen test. 3) Patients who had never been exposed to oxygen hyperbaria. Several hundred bacterials strains of the Streptococcus, Staphylococcus, Klebsiella and Nocardia genus were isolated from the material collected from the tested patients over intervals of a few days. The collected samples were when subjected to a detailed bacteriological analysis. At the same time bacteriological tests were performed at intervals on the hyperbaric atmosphere of the therapeutic pressure chamber, the walls of the chamber, and the masks used by the patients during the administration of hyperbaric oxygen. A certain degree of qualitative and quantitative changes (number reduction of bacterial strains) was observed. The authors attribute these results to the influence of hyperbaric oxygenation both on the microorganisms, as well as on a given patient's reactivity.

摘要

对以下三组患者进行了咽喉涂片的定性和定量细菌学检测

1)在2.2绝对大气压氧气条件下,每隔2至3天接受数次90分钟高压氧治疗的患者。2)在2.5绝对大气压氧气条件下接受单次30分钟高压氧治疗的患者/氧气测试。3)从未接受过高压氧治疗的患者。在几天的时间里,从受试患者采集的样本中分离出了数百株链球菌、葡萄球菌、克雷伯菌和诺卡氏菌属的细菌菌株。对采集的样本进行了详细的细菌学分析。同时,定期对治疗压力舱的高压环境、舱壁以及患者在接受高压氧治疗期间使用的面罩进行细菌学检测。观察到了一定程度的定性和定量变化(细菌菌株数量减少)。作者将这些结果归因于高压氧合对微生物以及特定患者反应性的影响。

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