Hatt P Y
Paroi Arterielle. 1980;6(3):129-32.
The hypertensive arteriopathy is the complication of any blood pressure augmentation, whatever its cause. It results from the association of: 1. Enlargement of arterial and arteriolar media, due to a double process of smooth muscle cells hypertrophy and hyperplasia, usually considered as secondary to arterial smooth muscle overworking. 2. Degenerative changes and fibrosis of the media likely due to exudative phenomena and transfer of blood throughout the arterial wall. 3. Initimal proliferation is constituted by cells which resemble to smooth muscle cells and are usually considered as cells coming from the media and invading the intima. 4. Exudation of several elements coming from the blood (fibrinogen, plasma globulins, red corpuscles) are the common denominator of accelerated hypertension.
高血压性动脉病是任何血压升高的并发症,无论其病因如何。它是由以下因素共同作用导致的:1. 动脉和小动脉中层的增大,这是由于平滑肌细胞肥大和增生的双重过程,通常被认为是动脉平滑肌过度工作的继发性结果。2. 中层的退行性改变和纤维化,可能是由于渗出现象以及血液在整个动脉壁中的渗透所致。3. 内膜增生由类似于平滑肌细胞的细胞构成,通常被认为是来自中层并侵入内膜的细胞。4. 血液中几种成分(纤维蛋白原、血浆球蛋白、红细胞)的渗出是急进型高血压的共同特征。