Gasparini M, Lombardi F
Recent Results Cancer Res. 1982;80:120-3. doi: 10.1007/978-3-642-81685-7_20.
At the Istituto Nazionale Tumori of Milan 60 patients with clinically localized Ewing's sarcoma were treated during 1965-1978 according to three different protocols. From 1965-1971, 18 patients received almost exclusively local therapy and 17 of 18 (94%) relapsed in a median time of 6 months. From 1971-1978 adjuvant chemotherapy according to two different drug schedules was employed after radiotherapy. Twenty-five of 42 (59%) are surviving and relapse-free at this time (follow-up 20-101 months).
在米兰国立肿瘤研究所,1965年至1978年间,60例临床局限性尤因肉瘤患者按照三种不同方案接受治疗。1965年至1971年,18例患者几乎仅接受局部治疗,18例中的17例(94%)复发,中位复发时间为6个月。1971年至1978年,放疗后采用两种不同药物方案进行辅助化疗。42例中的25例(59%)目前存活且无复发(随访20 - 101个月)。