Weiss R B, Tormey D C, Holland F, Weinberg V E, Lesnick G, Perloff M, Falkson G, Glidewell O J
Recent Results Cancer Res. 1982;80:170-6. doi: 10.1007/978-3-642-81685-7_28.
The Cancer and Leukemia Group B (CALB) has conducted a randomized study of adjuvant chemotherapy in patients with breast cancer who have involved axillary nodes at the time of mastectomy. Five-drug treatment (CMFVP) was compared with three-drug treatment (CMF). For patients with more than three involved nodes, the CMFVP regimen produced a significantly prolonged disease-free survival in comparison to the CMF regimen.
癌症与白血病B组（CALB）对在乳房切除术时腋窝淋巴结受累的乳腺癌患者进行了辅助化疗的随机研究。将五药治疗方案（CMFVP）与三药治疗方案（CMF）进行了比较。对于有三个以上受累淋巴结的患者，与CMF方案相比，CMFVP方案显著延长了无病生存期。
