Andresen J, Nielsen H E
Acta Orthop Scand. 1981 Oct;52(5):475-9. doi: 10.3109/17453678108992135.
Early radiologic signs and the radiologic course were examined retrospectively in 20 renal transplant patients who developed osteonecrosis after transplantation. Osteonecrosis appeared in 25 hips, 8 knees, 9 shoulders and 1 elbow. In most patients who developed osteonecrosis of the hip the early radiologic signs of osteonecrosis, with areas of lucencies and increased densities, were preceded by a thin fracture line in the immediate subchondral bone, parallel to the articular surface, appearing within a mean of 14 months after renal transplantation. This change seems to be a specific and very early finding in patients who subsequently develop osteonecrosis after renal transplantation. The initiation of collapsing phenomena of the articular surface was preceded by architectural changes near the articular surface wtih areas of lucencies and sclerosis. At the time of this investigation 26 per cent of the bones showed signs of regression of the changes with rebuilding of the former shape; 32 per cent showed progression and in 42 per cent the condition was stationary.
对20例肾移植后发生骨坏死的患者进行回顾性研究，观察其早期影像学表现及影像学病程。骨坏死出现在25个髋关节、8个膝关节、9个肩关节和1个肘关节。在大多数发生髋关节骨坏死的患者中，骨坏死的早期影像学表现为透亮区和密度增加，在此之前，紧邻关节面的软骨下骨出现一条与关节面平行的细骨折线，平均出现在肾移植后14个月。这种变化似乎是肾移植后发生骨坏死患者的一种特异性且非常早期的表现。关节面塌陷现象开始之前，关节面附近会出现透亮区和硬化区等结构改变。在本次调查时，26%的骨骼显示出病变消退并恢复原有形态的迹象；32%显示病变进展，42%的病情处于稳定状态。
