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鼠伤寒沙门氏菌中嘧啶对胞嘧啶脱氨酶的抑制作用。

Repression of cytosine deaminase by pyrimidines in Salmonella typhimurium.

作者信息

West T P, O'Donovan G A

出版信息

J Bacteriol. 1982 Mar;149(3):1171-4. doi: 10.1128/jb.149.3.1171-1174.1982.

DOI:10.1128/jb.149.3.1171-1174.1982
PMID:7037740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC216515/
Abstract

The synthesis of cytosine deaminase in Salmonella typhimurium is repressed by pyrimidines. This repression is mediated by both a uridine and a cytidine compound, indicating a distinct difference in the regulation of synthesis of cytosine deaminase from the regulation of the de novo pyrimidine pathway enzymes. A salvage role for the enzyme in pyrimidine metabolism is postulated.

摘要

鼠伤寒沙门氏菌中胞嘧啶脱氨酶的合成受嘧啶抑制。这种抑制作用由尿苷和胞苷化合物介导，这表明胞嘧啶脱氨酶合成的调控与从头嘧啶途径酶的调控存在明显差异。推测该酶在嘧啶代谢中具有补救作用。

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本文引用的文献

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Mutants of Escherichia coli requiring methionine or vitamin B12.需要甲硫氨酸或维生素B12的大肠杆菌突变体。
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Genetic analysis of pyrimidine mutants of Salmonella typhimurium.鼠伤寒沙门氏菌嘧啶突变体的遗传分析。
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Control of carbamyl phosphate synthesis in Salmonella typhimurium.鼠伤寒沙门氏菌中氨甲酰磷酸合成的调控
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Mutants of Salmonella typhimurium requiring cytidine for growth.鼠伤寒沙门氏菌中生长需要胞苷的突变体。
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Nucleoside-catabolizing enzymes in Salmonella typhimurium. Introduction by ribonucleosides.鼠伤寒沙门氏菌中的核苷分解代谢酶。由核糖核苷引发。
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Repression of enzyme synthesis of the pyrimidine pathway in Salmonella typhimurium.鼠伤寒沙门氏菌中嘧啶途径酶合成的抑制作用
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Mutants constitutive for nucleoside-catabolizing enzymes in Escherichia coli K12. Isolation, charactrization and mapping.大肠杆菌K12中核苷分解代谢酶组成型突变体。分离、表征与定位。
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