鼠伤寒沙门氏菌中嘧啶对胞嘧啶脱氨酶的抑制作用。
Repression of cytosine deaminase by pyrimidines in Salmonella typhimurium.
作者信息
West T P, O'Donovan G A
出版信息
J Bacteriol. 1982 Mar;149(3):1171-4. doi: 10.1128/jb.149.3.1171-1174.1982.
Abstract
The synthesis of cytosine deaminase in Salmonella typhimurium is repressed by pyrimidines. This repression is mediated by both a uridine and a cytidine compound, indicating a distinct difference in the regulation of synthesis of cytosine deaminase from the regulation of the de novo pyrimidine pathway enzymes. A salvage role for the enzyme in pyrimidine metabolism is postulated.
摘要
鼠伤寒沙门氏菌中胞嘧啶脱氨酶的合成受嘧啶抑制。这种抑制作用由尿苷和胞苷化合物介导，这表明胞嘧啶脱氨酶合成的调控与从头嘧啶途径酶的调控存在明显差异。推测该酶在嘧啶代谢中具有补救作用。
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