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Screening for mutants temperature sensitive in protein synthesis by using methionine analogues.

作者信息

Schmidt A, Bialer L, Ron E Z

出版信息

Mol Gen Genet. 1981;184(3):489-92. doi: 10.1007/BF00352528.

DOI:10.1007/BF00352528
PMID:7038397
Abstract

Two new mutants are described which are temperature sensitive in protein synthesis. The mutants were obtained by a screening procedure using methionine analogues. The method is based on two findings: a) that in E. coli, and in other members of the Enterobacteriaceae, sensitivity to methionine analogues increases with the growth temperature, and b) that cells which are not synthesizing proteins during treatment with methionine analogues have a shorter lag in resuming growth subsequent to removal of the analogue.

摘要

相似文献

1
Screening for mutants temperature sensitive in protein synthesis by using methionine analogues.
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2
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本文引用的文献

1
Mutants of Escherichia coli requiring methionine or vitamin B12.需要甲硫氨酸或维生素B12的大肠杆菌突变体。
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The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides.大肠杆菌中无细胞蛋白质合成对天然存在或合成的多聚核糖核苷酸的依赖性。
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3
[Incorporation of structural analogues of amino acids into bacterial proteins during their synthesis in vivo].
[在体内细菌蛋白质合成过程中氨基酸结构类似物掺入细菌蛋白质的情况]
Biochim Biophys Acta. 1959 Feb;31(2):378-91. doi: 10.1016/0006-3002(59)90011-3.
4
[Effects of structural analogues of amino acids on growth, protein synthesis, and enzyme synthesis in Escherichia coli].[氨基酸结构类似物对大肠杆菌生长、蛋白质合成及酶合成的影响]
Biochim Biophys Acta. 1959 Feb;31(2):347-56. doi: 10.1016/0006-3002(59)90007-1.
5
The formation of hydroxypyruvyl-tRNA.羟基丙酮酸 - 转运RNA的形成。
FEBS Lett. 1969 Aug;4(3):222-226. doi: 10.1016/0014-5793(69)80240-1.
6
Linkage map of Escherichia coli K-12, edition 6.大肠杆菌K-12连锁图谱,第6版。
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7
Growth rate of Escherichia coli at elevated temperatures: reversible inhibition of homoserine trans-succinylase.大肠杆菌在高温下的生长速率:高丝氨酸转琥珀酰酶的可逆抑制作用
J Bacteriol. 1971 Aug;107(2):397-400. doi: 10.1128/jb.107.2.397-400.1971.
8
Growth rate of Escherichia coli at elevated temperatures: limitation by methionine.大肠杆菌在高温下的生长速率:蛋氨酸的限制作用
J Bacteriol. 1971 Aug;107(2):391-6. doi: 10.1128/jb.107.2.391-396.1971.
9
Growth rate of Enterobacteriaceae at elevated temperatures: limitation by methionine.肠杆菌科细菌在高温下的生长速率:受甲硫氨酸限制
J Bacteriol. 1975 Oct;124(1):243-6. doi: 10.1128/jb.124.1.243-246.1975.
10
The gene for ribosomal protein L25 (rplY) maps at 47.3 min near nalA in Escherichia coli K-12.核糖体蛋白L25(rplY)基因位于大肠杆菌K-12中nalA附近47.3分钟处。
Mol Gen Genet. 1979 Nov;176(3):313-8. doi: 10.1007/BF00333093.