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核糖体蛋白L25（rplY）基因位于大肠杆菌K-12中nalA附近47.3分钟处。

The gene for ribosomal protein L25 (rplY) maps at 47.3 min near nalA in Escherichia coli K-12.

作者信息

Schnier J, Isono K

出版信息

Mol Gen Genet. 1979 Nov;176(3):313-8. doi: 10.1007/BF00333093.

DOI:10.1007/BF00333093
PMID:392236
Abstract

A temperature sensitive mutant, termed JE1306, derived from Escherichia coli strain PA3092 was found to have an alteration in the ribosomal protein L25. Crosses with various Hfr strains and transductions with P1 kc phage have revealed that the mutation maps at 47.3 min between nalA and fpk, in a region where no ribosomal protein gene has so far been located. The gene affected by this mutation is most probably the structural gene for protein L25 (rplY), because a strain heteromerozygous for the region shows both wild type and mutant forms of protein L25.

摘要

从大肠杆菌PA3092菌株衍生出的一个温度敏感突变体，命名为JE1306，被发现其核糖体蛋白L25发生了改变。与各种高频重组（Hfr）菌株的杂交以及用P1kc噬菌体进行的转导表明，该突变位于nalA和fpk之间47.3分钟处，在一个迄今为止尚未定位核糖体蛋白基因的区域。受此突变影响的基因很可能是蛋白L25（rplY）的结构基因，因为该区域的杂合子菌株同时显示出野生型和突变型的蛋白L25。

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引用本文的文献

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Screening for mutants temperature sensitive in protein synthesis by using methionine analogues.
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本文引用的文献

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Mutants of Escherichia coli requiring methionine or vitamin B12.需要甲硫氨酸或维生素B12的大肠杆菌突变体。
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Genetic fine structure of the pyrE region containing the genes for ribosomal proteins L28 and L33 in Escherichia coli.大肠杆菌中包含核糖体蛋白L28和L33基因的pyrE区域的遗传精细结构。
Mol Gen Genet. 1980;179(2):311-7. doi: 10.1007/BF00425458.
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Mapping of the gene for cytidine deaminase (cdd) in Escherichia coli K-12.大肠杆菌K-12中胞苷脱氨酶（cdd）基因的定位
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Cloning, characterization, and physical location of the rplY gene which encodes ribosomal protein L25 in Escherichia coli K12.大肠杆菌K12中编码核糖体蛋白L25的rplY基因的克隆、特性分析及物理定位。
Mol Gen Genet. 1991 Apr;226(1-2):341-4. doi: 10.1007/BF00273625.
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Mutants constitutive for nucleoside-catabolizing enzymes in Escherichia coli K12. Isolation, charactrization and mapping.大肠杆菌K12中核苷分解代谢酶组成型突变体。分离、表征与定位。
Eur J Biochem. 1972 May 23;27(2):208-15. doi: 10.1111/j.1432-1033.1972.tb01828.x.
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P1 transduction: formation of heterogenotes upon cotransduction of bacterial genes with a P2 prophage.
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Genetical analysis of fructose utilization by Escherichia coli.大肠杆菌利用果糖的遗传学分析。
Proc R Soc Lond B Biol Sci. 1974 Sep 17;187(1087):121-31. doi: 10.1098/rspb.1974.0066.
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10
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Mol Gen Genet. 1978 Oct 24;165(3):265-8. doi: 10.1007/BF00332525.