Bychkov S M
Vopr Med Khim. 1981 Nov-Dec;27(6):726-36.
Detailed studied on heparin, carried out within recent 3-5 years, are reviewed. Characterization of the chemical structure and physical parameters of heparin, data on conformation of the macromolecule of heparin and its biosynthesis are discussed. The proteoglycan localization in tissues and cells is also considered. Various functions of heparin are discussed on the basis of the current information. Perspectives of future research on heparin are summarized.
本文综述了近3至5年对肝素进行的详细研究。讨论了肝素的化学结构和物理参数的表征、肝素大分子构象及其生物合成的数据。还考虑了蛋白聚糖在组织和细胞中的定位。基于当前信息讨论了肝素的各种功能。总结了肝素未来研究的前景。