Largiadèr F, Baumgartner D, Uhlschmid G, Binswanger U
Dtsch Med Wochenschr. 1982 Apr 9;107(14):527-30.
In juvenile diabetics with diabetic nephropathy transplantation of the pancreas at the time of renal transplantation is thought to improve the progression of diabetic complications. Between 1. 7. 1980 and 31. 12. 1981, nine kidney and pancreas transplants were performed for this reason. Five pancreas transplantations failed for non-immunological causes. Of four successful transplantations, two transplants were later rejected through non-reversible immunological cause. The function of both organs has remained normal in two patients after 18 and 9 months, respectively. These patients are normoglycaemic on a normal diet and, despite prednisone medication, do not require insulin administration.
对于患有糖尿病肾病的青少年糖尿病患者,在进行肾移植时同时移植胰腺被认为可改善糖尿病并发症的进展。在1980年7月1日至1981年12月31日期间,出于这个原因进行了9例肾和胰腺联合移植手术。5例胰腺移植因非免疫性原因失败。在4例成功的移植手术中,有2例后来因不可逆的免疫性原因被排斥。分别在18个月和9个月后,两名患者的两个器官功能均保持正常。这些患者在正常饮食下血糖正常,尽管服用了泼尼松,但不需要注射胰岛素。