Thune P
Dermatologica. 1982 Jan;164(1):67-72. doi: 10.1159/000250068.
In a double-blind, cross-over trial with Tigason and placebo, the parameters of palmoplantar pustulosis underwent significant changes during the retinoid therapy. A hand-over effect was clearly indicated during the placebo period and several patients experienced long-lasting remissions.
在一项使用银屑灵(Tigason)和安慰剂的双盲交叉试验中,掌跖脓疱病的各项参数在维甲酸治疗期间发生了显著变化。在安慰剂期明显出现了交叉效应,并且有几位患者实现了长期缓解。