Andresen J H, Nielsen H E
Klin Wochenschr. 1982 Feb 15;60(4):199-205. doi: 10.1007/BF01715587.
The frequency of calcifications in vessels and soft tissue was 39% in 184 patients with chronic renal failure. Non-dialyzed patients and dialyzed patients at the start of dialysis treatment had most frequently calcifications of the aorta and larger vessels. Renal transplant recipients, who developed osteonecrosis or spontaneous fractures after transplantation, showed at the time of transplantation a higher frequency of calcifications compared to renal transplant recipients, who did not develop these complications. The frequency of calcifications increased with increasing age not only in the aorta, but also in the other vessels. In nondialyzed patients and in dialyzed patients at the start of dialysis treatment the calcifications were more commonly found in women and in renal transplant recipients in men. In all groups of patients a significant, higher frequency of calcifications was found in patients with radiologic evidence of bone resorption compared to patients without resorptive bone changes. Before and during chronic hemodialysis and following renal transplantation the frequency of calcifications increased. Calcification was most pronounced in the larger vessels in nondialyzed and dialyzed patients and in small vessels in renal transplant recipients. Increase in frequency of calcifications occurred slowly in nondialyzed patients and in renal transplant recipients, whereas an accelerated increase occurred in the first 15 months of the dialysis period in hemodialyzed patients.
184例慢性肾衰竭患者血管和软组织钙化的发生率为39%。未透析患者和开始透析治疗的透析患者主动脉和较大血管钙化最为常见。与未发生这些并发症的肾移植受者相比，移植后发生骨坏死或自发性骨折的肾移植受者在移植时钙化频率更高。钙化频率不仅在主动脉，而且在其他血管中都随着年龄的增长而增加。在未透析患者和开始透析治疗的透析患者中，女性和男性肾移植受者钙化更为常见。与无骨质吸收改变的患者相比，所有患者组中，有放射学证据显示骨质吸收的患者钙化频率显著更高。在慢性血液透析前、透析期间及肾移植后，钙化频率增加。未透析和透析患者的较大血管钙化最为明显，肾移植受者的小血管钙化最为明显。未透析患者和肾移植受者钙化频率增加缓慢，而血液透析患者在透析期的前15个月钙化频率加速增加。
