Malbran E S, Fernández-Meijide R E
Ophthalmology. 1982 Jan;89(1):38-40. doi: 10.1016/s0161-6420(82)34858-7.
A series of 105 penetrating grafts in keratoconus is analyzed. In 45 unilateral grafts, 15% developed allograft rejection (AR); in 30 bilateral grafts, there was AR in 13% of first eyes and in 17% of second eyes. The incidence of rejection in second eyes was three times greater within the first year after surgery than it was in first eyes. The interval between grafts performed on the first and second eyes demonstrates that with a mean interval of eight months, the incidence was 22%, and with a mean interval of 35 months, it was only 5%. None of the cases of AR caused definitive graft failure because of adequate warnings to the patient and prompt therapy. Visual acuity was 20/50 or better in the whole series in 91% of cases and 87% in the AR cases, it was the same in 87% of grafts.
分析了一系列105例圆锥角膜穿透性移植手术。在45例单侧移植中，15%发生了同种异体移植排斥反应（AR）；在30例双侧移植中，第一眼的AR发生率为13%，第二眼为17%。术后第一年，第二眼的排斥反应发生率比第一眼高三倍。第一眼和第二眼移植之间的间隔表明，平均间隔8个月时，发生率为22%，平均间隔35个月时，仅为5%。由于对患者有充分的警示并及时进行治疗，没有一例AR导致移植最终失败。在整个系列中，91%的病例视力达到20/50或更好，AR病例中这一比例为87%，87%的移植视力相同。
