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首次足月妊娠前口服避孕药及人工流产与乳腺癌风险的关系。

Oral contraceptive use and abortion before first term pregnancy in relation to breast cancer risk.

作者信息

Vessey M P, McPherson K, Yeates D, Doll R

出版信息

Br J Cancer. 1982 Mar;45(3):327-31. doi: 10.1038/bjc.1982.58.

DOI:10.1038/bjc.1982.58
PMID:7041938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2010930/
Abstract

A recent publication from California in this journal has suggested that both prolonged oral contraceptive use and abortion before first term pregnancy increases the risk of breast cancer in young women. Data are presented on 1176 women aged 16-50 years with breast cancer, interviewed in London or in Oxford, together with a like number of matches control subjects. The results are entirely reassuring, being, in fact, more compatible with protective effects than the reverse. Possible reasons for the differences between the 2 sets of data are discussed.

摘要

加州近期在本期刊上发表的一篇文章指出,长期使用口服避孕药以及首次怀孕前堕胎会增加年轻女性患乳腺癌的风险。文中呈现了1176名年龄在16至50岁之间患乳腺癌女性的数据,这些女性是在伦敦或牛津接受访谈的,同时还选取了数量相当的匹配对照对象。结果完全令人安心,事实上,这些结果更倾向于表明有保护作用而非相反情况。文中讨论了两组数据存在差异的可能原因。

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Oral contraceptive use and abortion before first term pregnancy in relation to breast cancer risk.首次足月妊娠前口服避孕药及人工流产与乳腺癌风险的关系。
Br J Cancer. 1982 Mar;45(3):327-31. doi: 10.1038/bjc.1982.58.
2
Oral contraceptive use and early abortion as risk factors for breast cancer in young women.口服避孕药的使用和早期流产作为年轻女性患乳腺癌的风险因素。
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本文引用的文献

1
Oral contraceptive use and early abortion as risk factors for breast cancer in young women.口服避孕药的使用和早期流产作为年轻女性患乳腺癌的风险因素。
Br J Cancer. 1981 Jan;43(1):72-6. doi: 10.1038/bjc.1981.10.
2
Breast cancer and oral contraceptives: findings in Oxford-Family Planning Association contraceptive study.乳腺癌与口服避孕药:牛津计划生育协会避孕研究的结果
Br Med J (Clin Res Ed). 1981 Jun 27;282(6282):2093-4. doi: 10.1136/bmj.282.6282.2093.
3
Oral contraceptives and breast neoplasia: a retrospective study.口服避孕药与乳腺肿瘤:一项回顾性研究。
Br Med J. 1972 Sep 23;3(5829):719-24. doi: 10.1136/bmj.3.5829.719.
4
Estimation of multiple relative risk functions in matched case-control studies.匹配病例对照研究中多个相对风险函数的估计。
Am J Epidemiol. 1978 Oct;108(4):299-307. doi: 10.1093/oxfordjournals.aje.a112623.
5
Contraceptive steroids and breast cancer.避孕甾体激素与乳腺癌
Br Med J. 1978 Apr 22;1(6119):1024-6. doi: 10.1136/bmj.1.6119.1024.
6
Oral contraceptives and breast cancer. Progress report of an epidemiological study.口服避孕药与乳腺癌。一项流行病学研究的进展报告。
Lancet. 1975 Apr 26;1(7913):941-3. doi: 10.1016/s0140-6736(75)92005-x.