[胃肠道人类癌组织中前列环素的形成（作者译）]
[Prostacyclin formation in human cancer tissue of the gastrointestinal tract (author's transl)].
作者信息
Gisinger C, Sinzinger H, Ferlitsch A, Seyfried H, Feigl W
出版信息
Wien Klin Wochenschr. 1981 Dec 11;93(23):717-20.
Prostacyclin synthesis was studied by means of bioassay in histologically classified biopsy material derived from the human gastrointestinal tract. Tumour tissue generated significantly more prostacyclin than normal tissue. Whether this enhanced PGI2 formation is due to an increased number of endothelial cells in tumour tissue, or represents a characteristic property of the tumour cell itself is not yet clear. This property could be used in future for the detection and control follow-up of malignant disease by means of radioimmunological determination of stabile metabolites as a tumour marker.
采用生物测定法，对取自人类胃肠道、经组织学分类的活检材料进行前列环素合成研究。肿瘤组织产生的前列环素明显多于正常组织。目前尚不清楚这种PGI2生成增强是由于肿瘤组织中内皮细胞数量增加，还是代表肿瘤细胞本身的一种特性。这种特性未来可用于通过放射免疫测定稳定代谢产物作为肿瘤标志物，来检测和控制恶性疾病的随访情况。
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