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The antimalarial activity of N-benzyl-oxydihydrotriazines. III. The activity of 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(2,4,5,-trichloropropyloxy)-1,3,5-triazine hydrobromide (BRL 51084) and hydrochloride (BRL 6231).

作者信息

Knight D J, Mamalis P, Peters W

出版信息

Ann Trop Med Parasitol. 1982 Feb;76(1):1-7.

PMID:7044322
Abstract
摘要

相似文献

1
The antimalarial activity of N-benzyl-oxydihydrotriazines. III. The activity of 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(2,4,5,-trichloropropyloxy)-1,3,5-triazine hydrobromide (BRL 51084) and hydrochloride (BRL 6231).N-苄基氧化二氢三嗪的抗疟活性。III. 4,6-二氨基-1,2-二氢-2,2-二甲基-1-(2,4,5-三氯丙氧基)-1,3,5-三嗪氢溴酸盐(BRL 51084)和盐酸盐(BRL 6231)的活性
Ann Trop Med Parasitol. 1982 Feb;76(1):1-7.
2
The antimalarial activity of N-benzyl-oxydihydrotriazines. IV. The development of resistance to BRL 6231 (4,6-diamino-1,2-dihyydro-2-,2-dimethyl-1-(2,4,5-trichloropropyloxy)-1,3,5 triazine hydrochloride) by Plasmodium berghei.N-苄基-氧化二氢三嗪的抗疟活性。IV. 伯氏疟原虫对BRL 6231(4,6-二氨基-1,2-二氢-2,2-二甲基-1-(2,4,5-三氯丙氧基)-1,3,5-三嗪盐酸盐)的抗性发展
Ann Trop Med Parasitol. 1982 Feb;76(1):9-14.
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The antimalarial activity of N-benzyloxydihydrotriazines. I. The activity of clociguanil (BRL 50216) against rodent malaria, and studies on its mode of action.N-苄氧基二氢三嗪的抗疟活性。I. 氯胍(BRL 50216)对啮齿动物疟疾的活性及其作用方式的研究。
Ann Trop Med Parasitol. 1980 Aug;74(4):393-404.
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The antimalarial activity of N-benzyloxydihydrotriazines. II. The development of resistance to clociguanil (BRL 50216) and cycloguanil by P. berghei.N-苄氧基二氢三嗪的抗疟活性。II. 伯氏疟原虫对氯胍(BRL 50216)和环氯胍的抗性发展。
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Babesia rodhaini and Plasmodium berghei. A highly active series of chlorophenoxyalkoxy-substituted diamino-dihydrotriazines against experimental infections in mice.罗得西亚巴贝斯虫和伯氏疟原虫。一系列对小鼠实验性感染具有高活性的氯苯氧基烷氧基取代二氨基二氢三嗪。
Ann Trop Med Parasitol. 1981 Feb;75(1):1-6.
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Antimalarial activity of 1-aryl-3,3-dialkyltriazenes.1-芳基-3,3-二烷基三氮烯的抗疟活性。
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[Antimalarial activities of hydroxypiperaquine and its phosphate against Plasmodium berghei and Plasmodium cynomolgi].羟哌喹及其磷酸盐对伯氏疟原虫和食蟹猴疟原虫的抗疟活性
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[Activity of 2 aminoglycoside antibiotics in Plasmodium berghei infection in Mus musculus].[两种氨基糖苷类抗生素对小家鼠伯氏疟原虫感染的活性]
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Antiparasitic agents. Part 7--Antimalarial activity of alkyl 5(6)-(4-aminophenyl) sulphonobenzimidazole-2-carbamates.抗寄生虫药。第7部分——5(6)-(4-氨基苯基)磺酰基苯并咪唑-2-氨基甲酸烷基酯的抗疟活性
Indian J Malariol. 1987 Jun;24(1):17-9.
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Antimalarial activity of tripynadine in mice and monkeys.曲匹萘定在小鼠和猴子体内的抗疟活性。
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Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil.用人类二氢叶酸还原酶进行转化会使疟原虫对WR99210不敏感,但不会影响氯胍的内在活性。
Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10931-6. doi: 10.1073/pnas.94.20.10931.
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In vitro activities of the biguanide PS-15 and its metabolite, WR99210, against cycloguanil-resistant Plasmodium falciparum isolates from Thailand.
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Antimicrob Agents Chemother. 1997 Oct;41(10):2300-1. doi: 10.1128/AAC.41.10.2300.