Lloveras J, Peterson P K, Simmons R L, Najarian J S
Arch Intern Med. 1982 May;142(5):888-92.
During an 11-year period, 1,069 patients received renal allografts at the University of Minnesota Hospital, Minneapolis, and infections developed in seven (0.65%) due to mycobacteria (Mycobacterium tuberculosis and M kansasii). The primary infection was in joint or subcutaneous tissue in six patients and pulmonary (miliary) in one. Infections in joint or skin shared common features regardless of the species of Mycobacterium and usually mimicked acute pyogenic bacterial infection; all responded to antimycobacterial drugs. The clinical manifestations in our patient in miliary tuberculosis were compared with those of 19 other patients described in the literature. Although their systemic manifestations were more severe, the symptoms were often ill-defined and the diagnosis overlooked. Five of these 20 patients (25%) died of uncontrolled infection.
在11年期间，明尼阿波利斯市明尼苏达大学医院有1069例患者接受了同种异体肾移植，其中7例（0.65%）因分枝杆菌（结核分枝杆菌和堪萨斯分枝杆菌）发生感染。6例患者的原发性感染发生在关节或皮下组织，1例为肺部（粟粒性）感染。无论分枝杆菌的种类如何，关节或皮肤感染都有共同特征，通常类似急性化脓性细菌感染；所有患者对抗分枝杆菌药物均有反应。将我们这位粟粒性肺结核患者的临床表现与文献中描述的其他19例患者的临床表现进行了比较。尽管他们的全身表现更为严重，但症状往往不明确，诊断被忽视。这20例患者中有5例（25%）死于无法控制的感染。
