脂肪细胞中胰岛素及胰岛素受体的内化与细胞内加工过程 - Suppr

Suppr

超能文献

Internalization and intracellular processing of insulin and insulin receptors in adipocytes.

作者信息

Olefsky J M, Marshall S, Berhanu P, Saekow M, Heidenreich K, Green A

出版信息

Metabolism. 1982 Jul;31(7):670-90. doi: 10.1016/0026-0495(82)90197-4.

DOI:10.1016/0026-0495(82)90197-4

PMID:7045573

Abstract

摘要

相似文献

Internalization and intracellular processing of insulin and insulin receptors in adipocytes.脂肪细胞中胰岛素及胰岛素受体的内化与细胞内加工过程

Metabolism. 1982 Jul;31(7):670-90. doi: 10.1016/0026-0495(82)90197-4.

Characterization of insulin-induced receptor loss and evidence for internalization of the insulin receptor.胰岛素诱导的受体丢失的特征及胰岛素受体内化的证据。

Diabetes. 1981 Sep;30(9):746-53. doi: 10.2337/diab.30.9.746.

Effects of lysosomotropic agents on insulin interactions with adipocytes. Evidence for a lysosomal pathway for insulin processing and degradation.溶酶体促渗剂对胰岛素与脂肪细胞相互作用的影响。胰岛素加工和降解的溶酶体途径的证据。

J Biol Chem. 1979 Oct 25;254(20):10153-60.

Internalization and degradation of a low affinity insulin ([LeuB24]insulin) by rat adipocytes.大鼠脂肪细胞对低亲和力胰岛素（[亮氨酸B24]胰岛素）的内化与降解

FEBS Lett. 1982 Aug 2;144(2):255-8. doi: 10.1016/0014-5793(82)80649-2.

Receptor mediated insulin degradation decreased by chloroquine in isolated rat adipocytes.在分离的大鼠脂肪细胞中，氯喹降低了受体介导的胰岛素降解。

J Biochem. 1980 Jul;88(1):39-44.

Metabolism of photoaffinity-labeled insulin receptors by adipocytes. Role of internalization, degradation, and recycling.脂肪细胞对光亲和标记胰岛素受体的代谢。内化、降解和再循环的作用。

J Biol Chem. 1984 May 25;259(10):6511-5.

Mechanisms of insulin degradation by isolated rat adipocytes.大鼠分离脂肪细胞胰岛素降解的机制

Mol Cell Biochem. 1982 Aug 20;47(1):23-9. doi: 10.1007/BF00241562.

Kinetics of insulin receptor internalization and recycling in adipocytes. Shunting of receptors to a degradative pathway by inhibitors of recycling.

J Biol Chem. 1985 Apr 10;260(7):4136-44.

Internalized insulin-receptor complexes are unidirectionally translocated to chloroquine-sensitive degradative sites. Dependence on metabolic energy.内化的胰岛素受体复合物单向转运至对氯喹敏感的降解位点。对代谢能量的依赖性。

J Biol Chem. 1988 Apr 25;263(12):5961-9.

Evidence for recycling of insulin receptors in isolated rat adipocytes.大鼠分离脂肪细胞中胰岛素受体再循环的证据。

J Biol Chem. 1981 Nov 25;256(22):11464-70.

引用本文的文献

Rapid insulin-dependent endocytosis of the insulin receptor by caveolae in primary adipocytes.原代脂肪细胞中，小窝介导胰岛素受体的快速胰岛素依赖性内吞作用。

PLoS One. 2009 Jun 19;4(6):e5985. doi: 10.1371/journal.pone.0005985.

Model-based hypothesis testing of key mechanisms in initial phase of insulin signaling.胰岛素信号传导初始阶段关键机制的基于模型的假设检验。

PLoS Comput Biol. 2008 Jun 20;4(6):e1000096. doi: 10.1371/journal.pcbi.1000096.

Quantitative studies of the rate of insulin internalization in isolated rat hepatocytes.对分离的大鼠肝细胞中胰岛素内化速率的定量研究。

Biochem J. 1984 Mar 1;218(2):307-12. doi: 10.1042/bj2180307.

Insulin receptors in isolated human adipocytes. Characterization by photoaffinity labeling and evidence for internalization and cellular processing.分离的人脂肪细胞中的胰岛素受体。通过光亲和标记进行表征及内化和细胞加工的证据。

J Clin Invest. 1983 Dec;72(6):1958-70. doi: 10.1172/JCI111160.

Absence of down-regulation of the insulin receptor by insulin. A possible mechanism of insulin resistance in the rat.胰岛素对胰岛素受体下调作用的缺失。大鼠胰岛素抵抗的一种可能机制。

Biochem J. 1983 Feb 15;210(2):373-8. doi: 10.1042/bj2100373.

Time-dependence of biological activity induced by covalent insulin-receptor complexes in rat adipocytes.大鼠脂肪细胞中由共价胰岛素受体复合物诱导的生物活性的时间依赖性。

Biochem J. 1985 Nov 15;232(1):49-53. doi: 10.1042/bj2320049.

Pathogenesis of impaired glucose tolerance and type II diabetes mellitus--current status.糖耐量受损和II型糖尿病的发病机制——现状

West J Med. 1985 Feb;142(2):219-29.

Cell-surface insulin receptor cycling and its implication in the glycogenic response in cultured foetal hepatocytes.细胞表面胰岛素受体循环及其在培养的胎儿肝细胞糖原生成反应中的意义。

Biochem J. 1986 Nov 1;239(3):609-15. doi: 10.1042/bj2390609.

Ultrastructural evidence for the accumulation of insulin in nuclei of intact 3T3-L1 adipocytes by an insulin-receptor mediated process.

Proc Natl Acad Sci U S A. 1987 Jan;84(2):459-63. doi: 10.1073/pnas.84.2.459.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验