de Jersey P, Wooller H O
Med J Aust. 1982 Mar 20;1(6):267-8. doi: 10.5694/j.1326-5377.1982.tb132296.x.
A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections. The symptomatic response was 73% for both drugs. Bacterial eradication was achieved in 81% and 100% of patients receiving cinoxacin and co-trimoxazole respectively. Three patients receiving co-trimoxazole stopped treatment because of adverse reactions. We conclude that cinoxacin is an effective and safe antibacterial agent in the treatment of urinary tract infections.
一项随机单盲临床试验将西诺沙星（每12小时500毫克）与复方新诺明（每12小时160毫克甲氧苄啶、800毫克磺胺甲恶唑）用于63例尿路感染患者的治疗进行了比较。两种药物的症状缓解率均为73%。接受西诺沙星和复方新诺明治疗的患者细菌清除率分别为81%和100%。3例接受复方新诺明治疗的患者因不良反应而停止治疗。我们得出结论，西诺沙星是治疗尿路感染的一种有效且安全的抗菌药物。
