Belisario C, Generoso M, Brandigi L, Menci R, Merello G, Ammanati V
Pediatr Med Chir. 1981 Sep-Oct;3(5):363-8.
The authors have examined the statistics of extracardiac malformations in infants with congenital heart disease, aged between birth and 12 months. Cases have been registered and studied within a period ranging from 1969 to 1979 at A. Meyer Hospital of Florence (Pediatric Institute of the University, Divisions of Medical Pediatrics and of Pediatric Surgery). Extracardiac abnormalities occur in 23,05% of infants seen during the first year of life for significant cardiac disease. Sometimes the extracardiac malformations are multiple and 66,3% of the affected infants have some established syndrome, especially chromosomal. The most frequent associated cardiac malformations are: ventricular septal defect (29,3%), complex heart disease (18,5%), non cyanotic heart disease with increased pulmonary blood flow (16,3%) and endocardial cushion defect (10,8%).
作者研究了出生至12个月大的先天性心脏病婴儿的心外畸形统计数据。1969年至1979年期间，在佛罗伦萨的A. 迈耶医院（大学儿科研究所，医学儿科学和小儿外科部门）对病例进行了登记和研究。在出生后第一年因严重心脏病就诊的婴儿中，23.05%存在心外异常。有时心外畸形是多发的，66.3%的患病婴儿有某种既定综合征，尤其是染色体综合征。最常见的相关心脏畸形是：室间隔缺损（29.3%）、复杂心脏病（18.5%）、肺血流量增加的非青紫型心脏病（16.3%）和心内膜垫缺损（10.8%）。
